Vincent Torre简介

Prof. Vincent Torre is currently Full Professor in Physiology at the International School for Advanced Studies (SISSA) Trieste in Italy. Vincent Torre has a background in Physics and Mathematics, but he has been working in Neuroscience for several decades. In his scientific career he has provided significant contributions at the interface between Physics and Neuroscience and has contributed to the development of a more quantitative Neuroscience and Computational Neuroscience. Vincent Torre is highly interdisciplinary and he has proved non trivial mathematical theorems (in the field of dynamical systems, complexity theory,…)  and opened new experimental methodologies (force measurements in neurons, SMFS in situ,…). He is the author of more than 150 MSs in peer reviewed journals and his H-index is close to 50, according Google Scholar.

· Biophysics of Phototransduction and of Ion Channels

From 1974, first under the supervision of Prof. Luigi Cervetto and then of Sir Alan Hodgkin, Vincent Torre has been studying phototransduction in its electrophysiological and quantitative aspects. In 1990 he also focused on the biophysical analysis of ion channels both from the theoretical and the experimental points of view.

· Systems and Computational Neuroscience

Since 1978, in collaboration with Tommy Poggio and Christof Koch, Vincent Torre has laid the basis for Computational Neuroscience with the production of several papers that now have become milestones in this field. In 1995 he started studying the leech nervous system and neuronal cultures, trying to combine experiments with theoretical methods, typically from physics and mathematics.

· Artificial Vision and Cybernetics

From the mid 1980s Vincent Torre has also studied Artificial Vision, giving important contributions to what is called “early vision“ and in particular to the perception of motion. At present Vincent Torre is Full Professor of Physiology within the Neurobiology Sector at SISSA and he is also the Director of the Interdisciplinary Laboratory at SISSA.

·Optical Tweezers Microscopy: applying and measuring piconewton forces in cell biology F. Difato, E. Ferrari, R. Shahapure, V. Torre and D. Cojoc

Chapter Book in Nanoscopy and Multidimensional Optical Fluorescence Microscopy; Editor: A. Diaspro, CRC Press, (2010).

·The role of dimensionality in neuronal network dynamics Ulloa Severino FP, Ban J, Song Q, Tang M, Bianconi G, Cheng G, Torre V.

Scientific Reports 6, Article number: 29640 (2016) doi:10.1038/srep29640

·Conformational rearrangements in the transmembrane domain of CNGA1 channels revealed by single-molecule force spectroscopy. Maity S, Mazzolini M, Arcangeletti M, Valbuena A, Fabris P, Lazzarino M, Torre V

Nat Commun. 2015 May 12;6:7093. doi: 10.1038/ncomms8093

·The phototransduction machinery in the rod outer segment has a strong efficacy gradient.t Mazzolini M, Facchetti G, Andolfi L, Proietti Zaccaria R, Tuccio S, Treu J, Altafini C, Di Fabrizio EM, Lazzarino M, Rapp G, Torre V.

Proc Natl Acad Sci U S A. 2015 May 4. pii: 201423162. [Epub ahead of print]

·A structural, functional, and computational analysis suggests pore flexibility as the base for the poor selectivity of CNG channels. Napolitano LM, Bisha I, De March M, Marchesi A, Arcangeletti M, Demitri N, Mazzolini M, Rodriguez A, Magistrato A, Onesti S, Laio A, Torre V.

Proc Natl Acad Sci U S A. 2015 Jul 7;112(27):E3619-28.

·Cdc42 and RhoA reveal different spatio-temporal dynamics upon local stimulation with Semaphorin-3A. Iseppon F, Napolitano LMR, Torre V and Cojoc D

Front. Cell. Neurosci. 9:333 (2015). DOI: 10.3389/fncel.2015.00333

·Nanomechanics Controls Neuronal Precursors Adhesion and Differentiation. Migliorini E, Ban J, Grenci G, Andolfi L, Pozzato A, Tormen M, Torre V and Lazzarino M.

Biotechnol Bioeng, 2013 Aug;110(8):2301-10.

·Common dynamical features of sensory adaptation in photoreceptors and olfactory sensory neurons.De Palo G, Facchetti G, Mazzolini M, Menini A, Torre V, Altafini C.

Scientific Reports 2013, 3, 1251.

·Comparison of the Force Exerted by Hippocampal and DRG Growth Cones. Amin L, Ercolini E, Ban J, Torre V.

PLoS One. 2013 Aug 21;8(8):e73025.

·Can Hippocampal Neurites and Growth Cones Climb over Obstacles? Lien TL, Ban J, Tormen M, Migliorini E, Grenci G, Pozzato A, Torre V.

PLoS One. 2013 Sep 6;8(9):e73966.

·The use of dendrograms to describe the electrical activity of motoneurons underlying behaviors in leeches. Juárez-Hernández LJ, Bisson G, Torre V

Front Integr Neurosci. 2013 Sep 27;7:69.

·The spontaneous electrical activity of neurons in leech ganglia. Moshtagh-Khorasani M, Miller EW, Torre V

Physiol Rep. 2013 Oct;1(5):e00089.

·Multiple mechanisms underlying rectification in retinal cyclic nucleotide-gated (CNGA1) channels. Arcangeletti M, Marchesi A, Mazzolini M, Torre V

Physiol Rep. 2013 Nov;1(6):e00148.

·Gating of CNG channels is voltage dependent. Marchesi A, Mazzolini M, Torre V.

Nature Communications 2012, 3, art. 973

·Less than 5 Netrin-1 molecules initiate attraction but 200 Sema3A molecules are necessary for repulsion. Giulietta Pinato, Dan Cojoc, Linh Thuy Lien, Alessio Ansuini, Jelena Ban, Elisa D’Este & Vincent Torre

Scientific Reports 2012, 2, 675

·A ring of threonines in the inner vestibule of the pore of CNGA1 channels constitutes a binding site for permeating ions.MARCHESI A, MAZZOLINI M, TORRE V

Journal of Physiology 2012, 590(20), 5075-5090

·The dynamics of group formation among leeches. BISSON G, BIANCONI G, TORRE V.

Frontiers in Physiology 2012, 3, 133

·The role of membrane stiffness and actin turnover on the force exerted by DRG lamellipodia.. AMIN L, ERCOLINI E, SHAHAPURE R, MIGLIORINI E, TORRE V.

Biophysical Journal 2012, 102(11), 2451-2460

·A component of retinal light adaptation mediated by the thyroid hormone cascade. Bedolla DE, Torre V.

PLoS One 2011, 6(10):e26334.

·Statistical characterization of social interactions and collective behavior in medicinal leeches. Bisson G, Torre V.

Journal of Neuroscience 2011, 106(1), 78-90

·Neuronal chemotaxis by optically manipulated liposomes. G. Pinato, L. T. Lien, E. D'Este, V. Torre & D. Cojoc

Journal of the European Optical Society - Rapid publications 2011, 6 , 11042 - 4 pages

·Acceleration of neuronal precursors differentiation induced by substrate nanotopography.. MIGLIORINI E, GRENCI G, BAN J, POZZATO A, TORMEN M, LAZZARINO M, TORRE V, RUARO ME

Biotechnol Bioengeneering 2011, 108 (11), 2736-2746

·Cytoskeletal actin networks in motile cells are critically self-organized systems synchronized by mechanical interactions.CARDAMONE L, LAIO A, TORRE V., SHAHAPURE R, DESIMONE A

PNAS 2011, 108 (84), 13978-13983

·Fragmentation as a mechanism for growth cone pruning and degeneration. BAN J, MIGLIORINI E, DI FOGGIA V, LAZZARINO M, RUARO ME, TORRE V.

Stem Cells and Development 2011, 20(6), 1031-1041

·The elementary events underlying force generation in neuronal lamellipodia. AMIN L, ERCOLINI E, SHAHAPURE R, BISSON G, TORRE V

.Scientific Reports 2011, 1, 153

·Force generation in lamellipodia is a probabilistic process with fast growth and retraction events. Shahapure R, Difato F, Laio A, Bisson G, Ercolini E, Amin L, Ferrari E, Torre V.

Biophysical Journal 2010, 98(6), 979-88

·Gating in CNGA1 channels. MAZZOLINI M, MARCHESI A, GIORGETTI A, TORRE V.

Pflügers Archiv - European Journal of Physiology 2010, 459 (4), 547-555

·Sequential steps underlying neuronal plasticity induced by a transient exposure to gabazine. PEGORARO S, BROCCARD FD, RUARO M.E, BIANCHINI D, AVOSSA D, PASTORE G, BISSON G, ALTAFINI C, TORRE V.

Journal of Cellular Physiology 2010, 222 (3), 713-728