Dan Cojoc简介

·1997 - PhD in Technical Physics - University “Politehnica” of Bucharest (UPB), RO

·1986 - Master in Precision Mechanics and Optical Engineering, UPB, RO

·1986-1990: Research Engineer at the Research Institute for Electronic Components, Bucharest.

·2003-2004: Full Professor; 2000-2003: Associate Professor; 1997-2000: Lecturer; 1990-1997: Assistant Professor for Applied Optics and Optical Information Processing courses at the Faculty of Mechanics and the Faculty of Electronics of the University “Politehnica” of Bucharest (UPB), RO.

·July 2004-present: Senior Scientist, Head of the Optical Manipulation Lab at CNR-IOM : the
Institute of Materials (IOM) of the Italian National Research Council (CNR), Trieste, Italy

· May -July 2008: visiting scientist, X-ray microscopy and SAXS, European Synchrotron
Radiation Facility (ESRF), Grenoble, FR

·Sept-Oct 2008: visiting scientist, X-ray diffraction and microscopy, Deutsches Elektronen Synchrotron (DESY), Hamburg, DE

·June 2000- June 2004: INFM associate researcher , diffractive optics design and nanofabrication, optical microscopy, Istituto Nazionale per la Fisica della Matteria INFM – TASC, Trieste, IT

· Mar - Apr 2000: visiting professor EU Tempus, optical information processing, Univ. of Valencia, Dept. of Optics, ES

·March – June 1999: visiting researcher RO-IT collaboration, image registration and pattern recognition, CNR – IEIIT, Torino, IT

· Nov 1997 – June 1998: visiting researcher, International Centre for Theoretical Physics (ICTP)
Trieste, TRIL program, image registration and pattern recognition vision project, CNR – IEIIT, Turin, IT.

·Jan - July 1996: visiting researcher Piemonte grant, diffractive optics for beam shaping, Politecnico di Torino, Dept. of Electronics, Turin, IT

· Apr – June 1994: visiting researcher EU Tempus, optical pattern recognition, Univ. of Valencia, Dept. of Optics, Valencia, ES.

With an initial background in Optics and Technical Physics Dan has been working in the fields of
Optics, Nanoscience and Biophotonics for more than 20 years. His scientific activity and skills are highly interdisciplinary. During his carreer he has developed advanced microscopy and spectroscopy instrumentation and techniques for applications in nanotechnology, biophysics, cancer cell and neurobiology.

The most important 10 contributions are:

· 1. show how glucose-coated magnetic nanops can be used for metabolic-based assays aimed at detecting and targeting cancer cells in:2016 - Scientific Reports 6, art. no. 21629; DOI: 10.1038/srep21629;

http://www.nature.com/s/srep21629

· 2. introduce new cell vertical indentation approach using optical tweezers to measure cancer cell stiffness complementary to AFM probing in: 2016 - Nanotechnology 27, art. no 065102; DOI: 10.1088/0957-4484/27/6/065102;

http://iopscience.iop.org//10.1088/0957-4484/27/6/065102

· 3. characterize the activation of small GTPases by local stimulation of the growth cones of neuronal cells and FRET microscopy in: 2015 - Frontiers Cell. Neuroscience 9, art. no 333; DOI: 10.3389/fncel.2015.00333;

http://journal.frontiersin.org//10.3389/fncel.2015.00333/abstract

· 4. pioneer speckle based technique and sensing device for fast detection of malaria in 2012 - Biomed. Opt. Express 3, 991-1005; DOI: 10.1364/BOE.3.000991;

https://www.osapublishing.org/boe/abstract.cfm?URI=boe-3-5-991

· 5. introduce a new local technique to stimulate different compartments of a neuronal cell with
very high spatial and temporal resolution in: 2012 - Scientific Reports 2, art. no. 00675; 2011; DOI: 10.1038/srep00675; and (Integrative Biology 3, 568-577) ; DOI: 10.1039/C0IB00102C;

http://www.nature.com/s/srep00675

http://pubs.rsc.org/en/content/landing/2011/ib/c0ib00102c#!divAbstract

· 6. design and implement a new device and optical manipulation approach for local analysis of
biological samples by micro-Small Angle X-ray Scattering SAXS with Synchrotron radiation microbeam in: 2011 Analytical Chemistry 83 4863-4870; DOI: 10.1021/ac200515x; http://pubs.acs.org/doi/abs/10.1021/ac200515x and 2010 - Appl. Phys. Lett. 97, art. no. 24410DOI: 10.1063/1.3525941;

http://scitation.aip.org/content/aip/journal/apl/97/24/10.1063/1.3525941 .

·7. design and implement a new optical tweezers technique to position and study bubble dynamics excited by ultrasounds in: 2009 - New J. of Phys. 11, art. no 013046; DOI: 10.1088/1367-2630/11/1/013046 and 2007 - Appl. Phys. Lett. 90, art. no 114103; DOI: 10.1063/1.2821245;

http://iopscience.iop.org//10.1088/1367-2630/11/1/013046

http://scitation.aip.org/content/aip/journal/apl/91/23/10.1063/1.2821245

·8. pioneer the optical tweezers force measurement technique to measure the force exerted by the filopodia and lamellipodia of the neuronal growth cones in: 2007 - PLoSONE 2, art. no. e1072; DOI: 10.1371/journal.pone.0001072;

http://journals.plos.org/plosone/?id=10.1371/journal.pone.0001072

·9. a new method to perform simultaneously three dimensional optical sectioning and optical manipulation of living cells in: 2005 - Opt. Express 5, 1395-1405; DOI: 10.1364/OPEX.13.001395;

https://www.osapublishing.org/oe/abstract.cfm?uri=oe-13-5-1395

·10. design and implementation of a new type of X-ray zone plate for phase contrast X-ray microscopy of biological samples in: 2003- Opt. Express 11, 2278-88; DOI: 10.1364/OE.11.002278;

https://www.osapublishing.org/oe/abstract.cfm?uri=oe-11-19-2278

· He has designed and implemented more than 15 optical tweezers microscopes and integrated them with microfluidics, force measurement, multi trapping, laser surgery for the study of biological samples as living cells in physiological conditions. 3 setups are running in the Optical Manipulation Lab at CNR-IOM, the others are located either in Italy (Trieste, Milan, Catanzaro) or abroad (France, Netherlands, Romania, Ghana, Venezuela). The results of his research activity have been presented in 135 publications. He organized 12 international schools and workshops in nanotechnology, biophotonics, super-resolution microscopy, optofluidics. Dan Cojoc is a reviewer for more than 10 journals in optics, physics and biophysics (e.g. Biomed. Opt. Express, Nat. Nanotech., Integr. Biol., Opt. Express, Nat. Comm.) and member of the editorial board for 3 other journals (Frontiers Nanotechnology, Journal of Optics and Int. J. of Optomechatronics). He has more than 30 invited talks at international workshops and conferences.;

· 126 papers in peer-reviewed journals and international conference proceedings; citations: 1640; H index: 22; i-10 index: 47.

· 11 books/chapter co-author/editor

· 2 international patents:

(1) E. Di Fabrizio, S. Cabrini, D. Cojoc, L. Businaro, Apparatus for determining the internal impression of the auditory canal, European Patent EP 1516157 A2, 23/03/2005

(2) E. Di Fabrizio, S. Cabrini, D. Cojoc, L. Businaro, An apparatus for determining the internal outline of a duct or cavity, and in particular for determining the internal impression of the auditory canal, a probe for thisapparatus, and a reflection device for an optical scanning apparatus, International Patent WO 2003105685 A2, 24/12/2003.

·1. 2017-2019: PI CNR-IOM of the PRO-FESR project on BIOPTICS (bacteria detection) – 110 k€ / 450 k€

·2. 2010 – 2014: CNR – IOM unit coordinator of the Italian Institute of Technology IIT-Seed project: MYOMAC - Myosin based machines project – 115 / 520 k€

·3. 2008 – 2011: CNR – IOM work package responsible (local optical delivery), European project NANOSCALE - Understanding interactions between cells and nanopatterned surfaces - 170 / 1.800 k€

·4. 2007 – 2010: CNR – IOM unit coordinator of the ESRF-CNR-Austrian Academy of Science collaboration project: Optical sample manipulation microscope for SAXS experimentst – 130 / 310 k€

·5. 2009 – 2012 CNR – IOM: researcher in the EU NFFA (Nanoscience Foundries & Fine Analysis) project, responsabile of the workpackage for sample manipulation withour mechanical contact.

·6. 2002 – 2004 INFM – TASC researcher in 2 national (PRIN and FIRB) projects on diffractive optics for X-Ray microscopy and optical tweezers.

·7. Univ. “Politehnica” of Bucharest – coordinator for two national research projects (1995-1997, 1998-1999) on optical pattern recognition.

·2007 - : faculty member of the PhD Course in Nanotechnology at the University of Trieste (UT).

·2013 - associate member of the PhD Course in Neurobiology at SISSA (International School for Advances Studies), Trieste, Italy.

·2008-2009, 2011-2012: professor with contract at the Faculty of Medicine UT, master in Nanobiotechnology.

·2000-2004Faculty member of the PhD course in Optoelectronics at the University “Politehnica” of Bucharest (UPB)-RO.

·Lecturer (1997-2000), associate professor (2000-2003), professor (2003-2004) at the UPBRO, for the courses: Applied Optics and Optical Information Processing at the Faculty of Mechanics and the Faculty of Electronics and Telecommunications.

·2013- present: lectures of Advanced Optical Microscopy at SISSA for the PhD students in Neurobiology

·2014 – present: lectures of Optical Microscopy for Nanotechnology at UT for the PhD students in Nanotechnology

·2011-2013, 2007-2009 – lectures of Optical Microscopy at UT, Faculty of Medicine, master Nanobiotechnology• 2014- present: lectures and lab of Optical Tweezers Microscopy for Neurobiology at SISSA, Summer School in Neurobiology

·1990 – 2004: courses of Technical Optics, Applied Optics, Optometry, Optical Information Processing and Fourier Optics at the faculties of Mechanics and Electronics UPB-RO – master and PhD program; conducted laboratory activities and supervised yearly projects.